Sync & Share Desktop Client

Hello,

is it possible do get access to a shared folder on a server via the desktop client and not only by the web client?

In my case, I want so save a file with a software in a folder at the server with a domain-user. In the next step, I want to open this file with the same software again on a different device with a differnet domain-user to make changes or just open it. 
In short: I just want an extra folder to be synced and shared in windows file system with the deskop client, so the software can access it.